Home / Blood Tests / Acid Phosphatase

Acid Phosphatase

The acid phosphatase test measures the level of the enzyme acid phosphatase in the blood. Acid phosphatase is produced by various tissues, but the prostate gland produces a significant amount. This test is mainly used to detect conditions related to the prostate, including prostate cancer, but it can also provide insight into bone, liver, and other diseases where tissue breakdown releases acid phosphatase into the bloodstream. Measuring acid phosphatase levels is crucial for diagnosing and monitoring certain conditions, particularly prostate cancer. Elevated levels of this enzyme can indicate the presence of prostate cancer that has spread (metastasized), especially to the bones. This test can also help detect other conditions, such as Paget's disease and Gaucher disease, where acid phosphatase levels may be elevated due to tissue damage. Indications for testing: - Prostate cancer monitoring: Especially if the cancer has spread beyond the prostate. - Bone disease diagnosis: To help detect conditions like Paget’s disease or metastatic cancer affecting the bones. - Liver disease or injury: To check for tissue damage releasing excess acid phosphatase into the bloodstream. - Gaucher disease: A genetic disorder affecting lipid storage that may cause elevated acid phosphatase levels. - Unexplained bone pain or fractures: To assess whether an underlying condition like metastasized cancer or bone disease is present. Fasting requirements No fasting required for the acid phosphatase test. However, it is essential to inform your healthcare provider of any medications or supplements you are taking, as some may affect enzyme levels. What can be detected - Prostate cancer: Especially in advanced stages where cancer has spread to bones or other organs. - Bone disorders: Such as Paget’s disease, where abnormal bone remodeling leads to enzyme release. - Liver diseases: Where tissue damage or inflammation causes higher levels of acid phosphatase. - Gaucher disease: A genetic disorder that affects the body’s ability to break down specific fats, leading to elevated enzyme levels. - Other cancers: Including certain cases of leukemia and lymphoma, where enzyme levels may be elevated due to abnormal cell activity. Monitoring acid phosphatase levels helps in the diagnosis and management of prostate cancer, especially in determining if the cancer has metastasized. While PSA is more commonly used, acid phosphatase remains valuable in specific cases. The test also aids in diagnosing bone and liver conditions, as well as rare genetic disorders like Gaucher disease. Timely detection through this test can lead to more targeted treatments and improved patient outcomes. By ensuring acid phosphatase testing is part of your diagnostic process, you can better monitor health conditions linked to abnormal enzyme activity, providing a more comprehensive view of your health.

There is an additional £20 phlebotomy fee for every donation.