Down Syndrome: PAPP-A Test (10-14 Week, 1st Trimester, NT) LIS Code: Down Syndrome P
Screen for Down syndrome risk in early pregnancy with the private PAPP-A blood test.
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About this test
What Is Pregnancy-Associated Plasma Protein A (PAPP-A)?
Pregnancy-associated plasma protein A (PAPP-A) is a protein produced by the outer layer of the developing placenta during early pregnancy. It plays a key role in regulating the growth and development of the fetus.
Importance of Nuchal Translucency Measurement
Nuchal translucency is a measurement taken during an early pregnancy ultrasound scan. It assesses the fluid-filled space at the back of the fetal neck and is used as a marker for chromosomal abnormalities.
Combined Screening for Trisomy 21 (Down’s Syndrome)
When PAPP-A and nuchal translucency results are combined with beta-human chorionic gonadotropin (β-hCG) levels, they provide a calculated risk assessment for chromosomal conditions such as Trisomy 21, commonly known as Down’s syndrome. This combined first-trimester screening helps in the early detection of potential genetic abnormalities.
Specialist PAPP-A Testing in Slough and Surrounding Areas
Pregnancy screening, including PAPP-A testing and nuchal translucency assessment, is available for individuals in Slough, Windsor, Langley, Maidenhead, and nearby locations. This is a specialist test—please contact the laboratory directly for full instructions and to arrange an appointment. Early screening in Slough supports informed prenatal care and reassurance for expectant parents.
