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Factor II / Prothrombin Mutation (G20210A)

The G20210A genetic test is a laboratory test that looks for a specific genetic mutation known as G20210A in the Factor II gene. The Factor II gene provides instructions for making a protein called prothrombin, which is involved in blood clotting. The G20210A mutation is associated with an increased risk of developing blood clots, such as deep vein thrombosis (DVT) or pulmonary embolism (PE). The G20210A genetic test is often used to identify individuals who are at an increased risk of developing blood clots, particularly those with a family history of blood clots or who have experienced a blood clot at a young age. It can also be used to help diagnose certain blood clotting disorders, such as Factor II deficiency or the rare condition known as antithrombin III deficiency.

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