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Homocysteine Mutation (MTHFR, C677T)

MTHFR C677T Genetic Test in Slough

What is the MTHFR Gene?
The MTHFR (methylenetetrahydrofolate reductase) gene provides the instructions for producing the MTHFR enzyme, which plays a key role in processing folate and converting homocysteine into methionine — a vital amino acid for numerous bodily functions.

Understanding the C677T Polymorphism
One of the most common variations in the MTHFR gene is known as the C677T polymorphism. This genetic change alters the amino acid structure of the enzyme, often resulting in reduced enzyme activity. Individuals with this mutation may have lower levels of folate and increased levels of homocysteine in the bloodstream.

Health Risks Associated with the C677T Variant
The presence of the C677T polymorphism can contribute to elevated homocysteine levels, which have been linked to various health conditions, including:

Cardiovascular disease

Increased stroke risk

Neural tube defects in infants born to women carrying the mutation

Other chronic health concerns involving folate metabolism

When to Consider MTHFR C677T Testing in Slough
Genetic testing for the MTHFR C677T variant is recommended for individuals in Slough and surrounding areas such as Windsor, Langley, and Maidenhead who:

Have a personal or family history of heart disease or stroke

Experience recurrent pregnancy loss or infertility

Have unexplained high homocysteine levels

Are planning a pregnancy and want to assess genetic risks

The Role of Diet and Lifestyle
While the C677T mutation may contribute to health risks, its effects are often influenced by external factors such as diet, vitamin B intake, and lifestyle habits. A balanced diet rich in folate and other B vitamins can help manage homocysteine levels even in the presence of this genetic variant.

Accurate Genetic Testing Available in Slough
Private clinics in Slough offer confidential and professional testing for the MTHFR C677T polymorphism. With no GP referral required, residents can access clear results and personalised health guidance.

Book Your MTHFR C677T Test in Slough Today
If you're concerned about genetic risks related to heart health, pregnancy, or homocysteine metabolism, book an MTHFR C677T test in Slough. Early detection allows for informed lifestyle changes and targeted nutritional support to manage associated health risks effectively.

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