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Lymphocyte Subsets (CD3/CD4/CD8)

The lymphocyte subsets (CD3/CD4/CD8) Test measures the levels of different types of T-cells in the blood, including helper T-cells (CD4), cytotoxic T-cells (CD8), and total T-cells (CD3). This test provides valuable insights into immune system health and is crucial for diagnosing and monitoring immune disorders, infections, and certain cancers. Why it is important to check these markers: Understanding the balance between different T-cell types helps identify immune deficiencies, monitor HIV progression, and assess the body’s ability to respond to infections or malignancies. Indications for testing: - HIV/AIDS monitoring: To track immune function and guide treatment decisions. - Immune deficiency evaluation: In patients with frequent infections or suspected immunodeficiency. - Autoimmune diseases: To understand immune regulation in conditions like lupus or rheumatoid arthritis. - Cancer assessment: In hematological cancers, to evaluate immune response and disease progression. - Transplant patients: To monitor for rejection or infection post-transplant. What can be detected: - Immunodeficiencies: Such as HIV/AIDS, where CD4 counts are significantly reduced. - Autoimmune conditions: Where abnormal T-cell levels may contribute to disease. - Cancer: Changes in T-cell populations may indicate hematological cancers or other malignancies. - Infections: Altered T-cell counts can signal chronic or acute infections affecting immune health. This test is a cornerstone in immunology, offering critical information for managing immune health, monitoring disease, and guiding therapies.

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