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Women's Health Checks

Depression Profile - Females

Explore hormonal and biochemical factors linked to low mood in women. The Depression Profile – Females helps assess hormone balance and mental wellbeing.

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Profile Price
£159
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Phlebotomy Fee: £25
A one-off £25 phlebotomy fee applies per visit — this covers your blood draw regardless of how many tests or profiles you book in the same appointment.

What's included in this profile

Estradiol (E2)
  • The main form of oestrogen in women of reproductive age
  • Used to assess ovarian function, fertility and menopause status
  • Also present at lower levels in men
Follicle-Stimulating Hormone (FSH)
  • A pituitary hormone that regulates egg/sperm production
  • Used to assess fertility and menopause status in women
  • Also checked in men to help assess sperm production
Free Thyroxine (FT4)
  • The active, unbound form of the main thyroid hormone T4
  • Checked alongside TSH to assess thyroid function
  • Helps confirm an over or underactive thyroid
Full Blood Count (FBC)
  • Measures red cells, white cells and platelets
  • A foundational test for overall health, anaemia and infection
  • The 'Differential' breaks white cells down by specific type
Glucose
  • The main sugar circulating in the blood, used for energy
  • Raised fasting levels can indicate prediabetes or diabetes
  • A cornerstone test for metabolic health
HDL Cholesterol
  • Often called 'good' cholesterol
  • Helps remove excess cholesterol from the bloodstream
  • Higher levels are generally protective for heart health
HbA1c (Glycated Haemoglobin)
  • Reflects average blood sugar levels over the past 23 months
  • The main test used to diagnose and monitor diabetes
  • Not affected by what you ate that day, unlike glucose
Luteinising Hormone (LH)
  • A pituitary hormone that triggers ovulation in women
  • Also plays a role in testosterone production in men
  • Checked alongside FSH for fertility and hormonal assessment
Progesterone (PRG)
  • A hormone that rises after ovulation to support early pregnancy
  • Used to confirm whether ovulation has occurred
  • Also monitored in early pregnancy
Rheumatoid Factor (RF)
  • An antibody associated with rheumatoid arthritis
  • Can also be positive in other autoimmune or chronic conditions
  • Interpreted alongside symptoms and other antibody tests
Thyroid-Stimulating Hormone (TSH)
  • The pituitary hormone that signals the thyroid to produce T3/T4
  • The primary firstline test for thyroid function
  • Raised or low levels suggest an underactive or overactive thyroid
Total Cholesterol
  • The overall amount of cholesterol in the blood
  • A key marker for cardiovascular risk
  • Interpreted alongside HDL, LDL and triglycerides
Vitamin B12
  • Essential for nerve function and red blood cell production
  • Deficiency can cause fatigue, tingling and memory issues
  • Common in vegetarians/vegans and older adults

About this profile

Sample Requirements:

Blood Sample

Turnaround Time:

4 hours

Special Instructions:

Fasting required (8-12 hours)

Depression Profile – Females

Comprehensive Blood Test for Hormonal, Thyroid, and Nutritional Imbalances Affecting Mental Health

The Depression Profile – Females is a specialised blood test designed to explore the physical factors that may be contributing to symptoms of depression in women. It provides a thorough analysis of hormone levels, thyroid function, key vitamin levels, and metabolic health – all of which can impact mood, energy, and mental clarity.

Why This Test Matters

Depression can stem from more than just emotional or psychological causes. In women, it’s often influenced by:

Hormonal fluctuations due to menstruation, pregnancy, menopause, or PCOS

Thyroid disorders such as hypothyroidism

Vitamin deficiencies, especially Vitamin B12

Metabolic issues including blood sugar or cholesterol imbalances

Understanding these underlying physical causes is essential for developing an effective and personalised approach to treatment.

What’s Included in the Test?

This profile checks for:

Reproductive hormones: Progesterone, Estradiol, FSH, LH

Thyroid function: TSH, Free T4 (and possibly Free T3)

Vitamin levels: Especially Vitamin B12

Metabolic markers: Glucose and Cholesterol levels

Who Should Consider This Test?

This test is ideal for women experiencing:

Persistent low mood, fatigue, or irritability

Mood changes linked to hormonal transitions (e.g. puberty, postpartum, menopause)

Suspected thyroid dysfunction or vitamin deficiencies

Difficulty concentrating or other symptoms of depression with no clear cause

Our Professional Services Our diagnostic testing is carried out by Medical Diagnosis, a UKAS ISO 15189 accredited laboratory, ensuring all results meet the highest UK standards of quality and accuracy. Clinical consultations and treatments, including Testosterone Replacement Therapy (TRT) and Weight Management programmes, are delivered through Medical Diagnosis Victoria, which is registered with the Care Quality Commission (CQC). All clinical services are provided by GMC-registered doctors with extensive experience, following thorough medical assessment in line with UK regulatory standards.
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