Depression Profile - Females
Explore hormonal and biochemical factors linked to low mood in women. The Depression Profile – Females helps assess hormone balance and mental wellbeing.
What's included in this profile
- The main form of oestrogen in women of reproductive age
- Used to assess ovarian function, fertility and menopause status
- Also present at lower levels in men
- A pituitary hormone that regulates egg/sperm production
- Used to assess fertility and menopause status in women
- Also checked in men to help assess sperm production
- The active, unbound form of the main thyroid hormone T4
- Checked alongside TSH to assess thyroid function
- Helps confirm an over or underactive thyroid
- Measures red cells, white cells and platelets
- A foundational test for overall health, anaemia and infection
- The 'Differential' breaks white cells down by specific type
- The main sugar circulating in the blood, used for energy
- Raised fasting levels can indicate prediabetes or diabetes
- A cornerstone test for metabolic health
- Often called 'good' cholesterol
- Helps remove excess cholesterol from the bloodstream
- Higher levels are generally protective for heart health
- Reflects average blood sugar levels over the past 23 months
- The main test used to diagnose and monitor diabetes
- Not affected by what you ate that day, unlike glucose
- A pituitary hormone that triggers ovulation in women
- Also plays a role in testosterone production in men
- Checked alongside FSH for fertility and hormonal assessment
- A hormone that rises after ovulation to support early pregnancy
- Used to confirm whether ovulation has occurred
- Also monitored in early pregnancy
- An antibody associated with rheumatoid arthritis
- Can also be positive in other autoimmune or chronic conditions
- Interpreted alongside symptoms and other antibody tests
- The pituitary hormone that signals the thyroid to produce T3/T4
- The primary firstline test for thyroid function
- Raised or low levels suggest an underactive or overactive thyroid
- The overall amount of cholesterol in the blood
- A key marker for cardiovascular risk
- Interpreted alongside HDL, LDL and triglycerides
- Essential for nerve function and red blood cell production
- Deficiency can cause fatigue, tingling and memory issues
- Common in vegetarians/vegans and older adults
About this profile
Sample Requirements:

Turnaround Time:
4 hours
Special Instructions:
Fasting required (8-12 hours)
Depression Profile – Females
Comprehensive Blood Test for Hormonal, Thyroid, and Nutritional Imbalances Affecting Mental Health
The Depression Profile – Females is a specialised blood test designed to explore the physical factors that may be contributing to symptoms of depression in women. It provides a thorough analysis of hormone levels, thyroid function, key vitamin levels, and metabolic health – all of which can impact mood, energy, and mental clarity.
Why This Test Matters
Depression can stem from more than just emotional or psychological causes. In women, it’s often influenced by:
Hormonal fluctuations due to menstruation, pregnancy, menopause, or PCOS
Thyroid disorders such as hypothyroidism
Vitamin deficiencies, especially Vitamin B12
Metabolic issues including blood sugar or cholesterol imbalances
Understanding these underlying physical causes is essential for developing an effective and personalised approach to treatment.
What’s Included in the Test?
This profile checks for:
Reproductive hormones: Progesterone, Estradiol, FSH, LH
Thyroid function: TSH, Free T4 (and possibly Free T3)
Vitamin levels: Especially Vitamin B12
Metabolic markers: Glucose and Cholesterol levels
Who Should Consider This Test?
This test is ideal for women experiencing:
Persistent low mood, fatigue, or irritability
Mood changes linked to hormonal transitions (e.g. puberty, postpartum, menopause)
Suspected thyroid dysfunction or vitamin deficiencies
Difficulty concentrating or other symptoms of depression with no clear cause