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Depression Profile

Depression Profile - Male

Discover the root cause of mood changes with our Depression Profile for Men. This hormone and wellness blood test helps identify imbalances linked to male depression and fatigue. Book your test online at Vitalync Diagno…

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Phlebotomy Fee: £25
A one-off £25 phlebotomy fee applies per visit — this covers your blood draw regardless of how many tests or profiles you book in the same appointment.

What's included in this profile

Estradiol (E2)
  • The main form of oestrogen in women of reproductive age
  • Used to assess ovarian function, fertility and menopause status
  • Also present at lower levels in men
Follicle-Stimulating Hormone (FSH)
  • A pituitary hormone that regulates egg/sperm production
  • Used to assess fertility and menopause status in women
  • Also checked in men to help assess sperm production
Free Thyroxine (FT4)
  • The active, unbound form of the main thyroid hormone T4
  • Checked alongside TSH to assess thyroid function
  • Helps confirm an over or underactive thyroid
Full Blood Count (FBC)
  • Measures red cells, white cells and platelets
  • A foundational test for overall health, anaemia and infection
  • The 'Differential' breaks white cells down by specific type
Glucose
  • The main sugar circulating in the blood, used for energy
  • Raised fasting levels can indicate prediabetes or diabetes
  • A cornerstone test for metabolic health
HDL Cholesterol
  • Often called 'good' cholesterol
  • Helps remove excess cholesterol from the bloodstream
  • Higher levels are generally protective for heart health
HbA1c (Glycated Haemoglobin)
  • Reflects average blood sugar levels over the past 23 months
  • The main test used to diagnose and monitor diabetes
  • Not affected by what you ate that day, unlike glucose
Luteinising Hormone (LH)
  • A pituitary hormone that triggers ovulation in women
  • Also plays a role in testosterone production in men
  • Checked alongside FSH for fertility and hormonal assessment
Progesterone (PRG)
  • A hormone that rises after ovulation to support early pregnancy
  • Used to confirm whether ovulation has occurred
  • Also monitored in early pregnancy
Rheumatoid Factor (RF)
  • An antibody associated with rheumatoid arthritis
  • Can also be positive in other autoimmune or chronic conditions
  • Interpreted alongside symptoms and other antibody tests
Testosterone
  • The primary male sex hormone, also present in women
  • Affects energy, muscle mass, libido and mood
  • Low levels in men can cause fatigue and reduced sex drive
Thyroid-Stimulating Hormone (TSH)
  • The pituitary hormone that signals the thyroid to produce T3/T4
  • The primary firstline test for thyroid function
  • Raised or low levels suggest an underactive or overactive thyroid
Total Cholesterol
  • The overall amount of cholesterol in the blood
  • A key marker for cardiovascular risk
  • Interpreted alongside HDL, LDL and triglycerides
Vitamin B12
  • Essential for nerve function and red blood cell production
  • Deficiency can cause fatigue, tingling and memory issues
  • Common in vegetarians/vegans and older adults

About this profile

Depression Profile – Males

A Comprehensive Blood Test for Identifying Biological Factors Linked to Depression

The Depression Profile – Males is a specialized blood test designed to assess biological contributors to depression in men. By analyzing hormone levels, thyroid function, nutrient status, and metabolic markers, this test helps uncover underlying imbalances that may influence mood and mental well-being. It provides valuable insights to support a holistic approach to mental health care.

Understanding Depression in Men

Depression is a common mental health condition that often manifests differently in men. Symptoms may include persistent sadness, low energy, irritability, difficulty concentrating, and changes in sleep or appetite. While psychological and environmental factors play a role, biological imbalances—such as low testosterone, thyroid dysfunction, and nutrient deficiencies—can significantly impact mood and overall well-being. Identifying and addressing these factors is key to effective management and treatment.

Who Should Consider This Test?

This test is recommended for men who:

  • Experience persistent depressive symptoms, such as low energy, sadness, or reduced libido.
  • Suspect hormonal or thyroid imbalances may be affecting their mental health.
  • Want to explore biological factors contributing to depression, particularly if traditional treatments have been ineffective.

What This Test Evaluates

The Depression Profile – Males assesses:

  • Hormonal Balance: Measures testosterone, estrogen, and progesterone levels, which influence mood, cognitive function, and emotional well-being.
  • Thyroid Function: Evaluates thyroid-stimulating hormone (TSH) and free thyroxine (FT4) levels, as thyroid dysfunction is often linked to depression.
  • Nutrient Deficiencies: Identifies low levels of vitamin B12, which is essential for brain function and energy metabolism.
  • Metabolic Health: Analyzes glucose and cholesterol levels to detect potential insulin resistance or cardiovascular risks that may contribute to mood disturbances.

Fasting Requirements

To ensure accurate glucose and lipid measurements, fasting for 8–10 hours before the test is required. Follow any additional instructions from your healthcare provider for the most accurate results.

Test Details

  • Sample Required: Blood sample
  • Results Available: Approximately 4 hours

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Our Professional Services Our diagnostic testing is carried out by Medical Diagnosis, a UKAS ISO 15189 accredited laboratory, ensuring all results meet the highest UK standards of quality and accuracy. Clinical consultations and treatments, including Testosterone Replacement Therapy (TRT) and Weight Management programmes, are delivered through Medical Diagnosis Victoria, which is registered with the Care Quality Commission (CQC). All clinical services are provided by GMC-registered doctors with extensive experience, following thorough medical assessment in line with UK regulatory standards.
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