The Hepatitis B Profile is a specialized blood test designed to determine exposure, immunity, and active infection status of the Hepatitis B virus (HBV). It helps diagnose acute or chronic infection, assess vaccination response, and monitor liver health in individuals at risk of or affected by Hepatitis B.
What is Hepatitis B?
Hepatitis B is a viral infection that targets the liver and is transmitted through contact with infected blood, semen, or bodily fluids. The virus can cause both short-term (acute) and long-term (chronic) infections. Symptoms often include fatigue, jaundice, nausea, and abdominal pain. Chronic infection can lead to liver cirrhosis, liver failure, or cancer. Early detection and regular monitoring are vital for effective management and preventing long-term complications.
Who is this profile for?
This test is recommended for individuals who:
Have symptoms of liver dysfunction such as yellowing of the eyes, fatigue, or abdominal pain.
Have been exposed to the virus through contact with infected individuals or bodily fluids.
Require routine screening for employment, travel, or medical clearance.
Are pregnant, to prevent mother-to-child transmission.
Need to confirm immunity following vaccination or monitor an existing Hepatitis B infection.
What can be detected?
The Hepatitis B Profile evaluates key markers to determine infection stage, immunity, and viral activity:
Hepatitis B Surface Antigen (HBsAg): Indicates current infection (acute or chronic).
Hepatitis B Surface Antibody (Anti-HBs): Confirms immunity due to vaccination or recovery from past infection.
Hepatitis B Core Antibody Total (Anti-HBc Total): Detects previous or ongoing infection.
Hepatitis B Core IgM Antibody (Anti-HBc IgM): Identifies recent or acute infection.
Hepatitis B e Antigen (HBeAg): Indicates active viral replication and higher infectivity.
Hepatitis B e Antibody (Anti-HBe): Suggests a lower level of viral replication or recovery phase.
When to get tested
Testing is recommended if you experience symptoms such as fatigue, nausea, or jaundice, or if you have been exposed to someone with Hepatitis B. It is also suitable for individuals undergoing health checks, vaccine verification, or long-term liver monitoring.
Fasting requirements
No fasting is required before taking this test. Follow any preparation guidelines provided by your healthcare provider.
Key benefits
The Hepatitis B Profile offers a complete analysis of infection status, immunity, and viral activity. It aids in accurate diagnosis, effective management, and monitoring of treatment outcomes, ensuring timely intervention and improved liver health.
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Our partner, Medical Diagnosis, is UKAS 15189 accredited and registered with the CQC. All tests are conducted to the highest standards of accuracy and reliability.
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