Weight Loss / GLP-1 Profile Plus LIS Code: NW-14
Monitor your metabolic, nutrient, and organ health with the Weight Loss / GLP-1 Profile Plus at Vitalync Diagnosis. Ideal for individuals using GLP-1 medications or following structured weight loss programmes.
What's included in this profile
- An enzyme found mainly in the liver
- Raised levels can indicate liver inflammation or damage
- Commonly checked alongside AST to assess liver health
- An enzyme produced by the pancreas and salivary glands
- Helps digest carbohydrates
- Raised levels can indicate pancreatitis or other pancreatic issues
- An enzyme found in the liver, heart and muscles
- Raised levels can suggest liver or muscle damage
- Used alongside ALT to help pinpoint the cause of liver stress
- A waste product from normal muscle breakdown, filtered by the kidneys
- Raised levels can indicate reduced kidney function
- Used to calculate eGFR (estimated kidney filtration rate)
- The active, unbound form of the main thyroid hormone T4
- Checked alongside TSH to assess thyroid function
- Helps confirm an over or underactive thyroid
- Measures red cells, white cells and platelets
- A foundational test for overall health, anaemia and infection
- The 'Differential' breaks white cells down by specific type
- An enzyme sensitive to liver and bile duct problems
- Often raised with alcohol intake or bile flow issues
- Helps confirm whether a raised ALP is liverrelated
- Often called 'good' cholesterol
- Helps remove excess cholesterol from the bloodstream
- Higher levels are generally protective for heart health
- Reflects average blood sugar levels over the past 23 months
- The main test used to diagnose and monitor diabetes
- Not affected by what you ate that day, unlike glucose
- Often called 'bad' cholesterol
- Can build up in artery walls, raising heart disease risk
- A key target for lifestyle or treatment intervention
- A hormone made by fat cells that regulates appetite
- Levels generally rise with increased body fat
- Sometimes checked in metabolic or weightrelated assessments
- An enzyme produced by the pancreas to help digest fats
- A more specific marker than amylase for pancreatic problems
- Raised levels often indicate pancreatitis
- The pituitary hormone that signals the thyroid to produce T3/T4
- The primary firstline test for thyroid function
- Raised or low levels suggest an underactive or overactive thyroid
- A breakdown product of old red blood cells, processed by the liver
- Raised levels can cause jaundice (yellowing of skin/eyes)
- Helps assess liver function and red cell turnover
- The overall amount of cholesterol in the blood
- A key marker for cardiovascular risk
- Interpreted alongside HDL, LDL and triglycerides
- A type of fat found in the blood, from food and the liver
- Raised levels are linked to heart disease and metabolic conditions
- Affected by diet, alcohol and blood sugar control
- A waste product from protein breakdown, filtered by the kidneys
- Raised levels can indicate reduced kidney function or dehydration
- Interpreted alongside creatinine for a fuller picture
- A waste product from the breakdown of purines in food and cells
- Raised levels are linked to gout and kidney stones
- Also checked as part of general metabolic screening
- Essential for nerve function and red blood cell production
- Deficiency can cause fatigue, tingling and memory issues
- Common in vegetarians/vegans and older adults
- Essential for bone health, calcium absorption and immunity
- Deficiency is common, especially in winter months
- One of the most frequently tested vitamins in the UK
- An estimate of how well the kidneys are filtering blood
- Calculated from creatinine, age and sex
- The key measure used to stage kidney function
About this profile
The Weight Loss / GLP-1 Profile Plus is an advanced health assessment designed for individuals using or planning to use GLP-1 receptor agonists for weight loss or diabetes management. These medications, while effective, can influence vitamin levels, liver enzymes, thyroid hormones, and kidney function. This enhanced panel provides a deeper insight into your overall metabolic and nutritional status by including additional markers such as Vitamin B12, Vitamin D, and Leptin — ensuring your weight loss journey remains safe, balanced, and medically supervised.
Who is this test for?
This profile is ideal for individuals who:
– Are using or preparing to start GLP-1-based treatments such as semaglutide, liraglutide, or tirzepatide.
– Want to monitor the internal health effects of weight loss and medication use.
– Are managing obesity, metabolic syndrome, pre-diabetes, or type 2 diabetes.
– Wish to check for nutritional deficiencies, especially Vitamin D or B12, during weight reduction.
– Are looking to track hormonal, metabolic, and organ health while following a structured or medically guided programme.
What can be detected?
Vitamin and Nutrient Status:
– Vitamin B12: Essential for energy, red blood cell production, and nerve health; may decrease due to dietary restriction or medication use.
– Vitamin D (25-OH): Supports bone strength, immunity, and metabolic regulation.
– Leptin: A hormone that controls appetite and fat metabolism; imbalances can affect weight management outcomes.
Glucose and Metabolic Function:
– HbA1c: Measures average blood sugar levels over the last 2–3 months; vital for monitoring insulin sensitivity and diabetes risk.
Liver and Pancreatic Function:
– ALT, AST, Gamma-GT, Bilirubin: Assess liver enzyme activity and detect inflammation or liver stress.
– Amylase, Lipase: Evaluate pancreatic health and help detect signs of pancreatic inflammation.
Kidney Health:
– Urea, Creatinine, Uric Acid, eGFR: Measure kidney efficiency and waste filtration performance.
Thyroid Function:
– Thyroid-Stimulating Hormone (TSH) and Free Thyroxine (FT4): Evaluate thyroid regulation of metabolism and energy balance.
Lipid and Cardiovascular Health:
– Total Cholesterol, HDL, LDL, Triglycerides: Provide a detailed picture of heart health and fat metabolism.
Blood Health:
– Full Blood Count (FBC): Analyses red and white blood cells and platelets to assess overall health, immunity, and oxygen-carrying capacity.
Fasting requirements
Fasting for 8–12 hours is recommended to ensure accurate glucose and lipid measurements. Only water is allowed during this period.
