α1-Antitrypsin LIS Code: A1-AT
Private alpha-1 antitrypsin (AAT) blood test £26: checks for inherited AAT deficiency, which can affect the lungs and liver. No GP referral. Slough, Victoria, Neasden.
Before your test
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About this test
Alpha-1 antitrypsin (AAT) is a protein made by the liver that protects the lungs from damage caused by the body's own inflammation. Some people inherit a faulty version of the gene that makes it, which leads to alpha-1 antitrypsin deficiency. Low levels leave the lungs less protected and can also affect the liver.
Who has an AAT test
- People with COPD or emphysema diagnosed at a young age (under about 45), or who have never smoked or smoked very little.
- People with asthma that doesn't respond well to usual treatment, or with bronchiectasis.
- Adults or children with unexplained liver disease or raised liver enzymes.
- Close relatives of someone with AAT deficiency, as it runs in families.
What your result means
- Normal level: deficiency is unlikely.
- Low level: suggests AAT deficiency. It's usually confirmed with genetic testing that shows which form of the gene you carry, arranged through your doctor or a specialist.
- Something to know: AAT rises during infection, inflammation, pregnancy and with some hormone treatments, so a borderline result can look normal at those times. Testing CRP at the same time shows whether inflammation could be affecting the result.
If you have AAT deficiency, not smoking is the single most important step to protect your lungs, and your doctor may suggest regular lung and liver checks. A liver function profile is a useful companion test.
How it works at VitaLync
- £26 for the test, plus a £25 blood draw at our Slough, Victoria or Neasden clinic, or a nurse visit at home or work.
- No fasting is needed, and you can book any time of day.
- The laboratory usually reports AAT within about 7 days, and your result appears in your secure online account.
- To talk your result through, book a GP consultation.