Antismooth Muscle Antibodies (ASMA) LIS Code: ASMA
Private anti-smooth muscle antibody (ASMA) blood test £43, used to check for autoimmune hepatitis. No fasting or GP referral. Slough, Victoria, Neasden.
Before your test
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About this test
Anti-smooth muscle antibodies (ASMA) are antibodies your immune system can make against a protein found in smooth muscle and liver cells. The test is mainly used to look for autoimmune hepatitis, a condition where the immune system attacks the liver.
When it's used
- Raised liver enzymes (ALT or AST) on a liver function test, especially when there's no obvious cause such as alcohol, a fatty liver or a viral infection.
- Symptoms of liver inflammation, such as tiredness, discomfort under the right ribs, dark urine or yellowing of the skin or eyes.
- Alongside other autoimmune tests, when another autoimmune condition such as thyroid disease or coeliac disease is already known.
What your result means
- Negative: autoimmune hepatitis is less likely, although a small number of people with it don't have these antibodies.
- Positive, at a high level: supports a diagnosis of autoimmune hepatitis, particularly with raised liver enzymes. A specialist usually confirms it with further tests.
- Positive, at a low level: fairly common after a recent viral infection and in some other conditions, so a low result on its own isn't a diagnosis.
ASMA is usually tested with antinuclear antibodies (ANA) and antimitochondrial antibodies (AMA), which help tell autoimmune hepatitis apart from other autoimmune liver conditions, and with a liver function profile.
How it works at VitaLync
- £43 for the test, plus a £25 blood draw at our Slough, Victoria or Neasden clinic, or a nurse visit at home or work.
- No fasting and you can book any time of day.
- The laboratory usually reports ASMA within about 7 days, and your result appears in your secure online account.
- If your result is positive or your liver tests are raised, book a GP consultation to plan next steps.