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Phosphates Inorganic

88% of the phosphorus contained in the body is localized in bones. Phosphorus occurs in blood in the form of inorganic phosphate and in organically bound phosphoric acid. The ratio of phosphate to calcium in the blood is approximately 6:10. An increase in the level of phosphorus causes a decrease in the calcium level. The mechanism is influenced by interactions between parathormone and vitamin D. Hypoparathyroidism, vitamin D intoxication and renal failure with decreased glomerular phosphate filtration give rise to hyperphosphatemia. Hypophosphatemia occurs in rickets, hyperparathyroidism and Fanconi’s syndrome.

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