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Vitamin D 1,25 2-OH

Importance of Vitamin D for Bone Health

Vitamin D plays a vital role in maintaining healthy bones. In children, a severe deficiency can cause rickets—a condition that results in bone deformities due to poor mineralisation. Even mild deficiencies can impair the body’s ability to absorb and utilise dietary calcium effectively, compromising bone strength and development.

Muscle Function and Fall Risk in the Elderly

Vitamin D deficiency has been closely linked to muscle weakness, particularly in older adults. This muscle impairment increases the risk of falls, highlighting the importance of maintaining adequate vitamin D levels in the elderly population to support mobility and prevent injury.

Link Between Vitamin D Deficiency and Secondary Hyperparathyroidism

Insufficient vitamin D is a frequent cause of secondary hyperparathyroidism. Elevated parathyroid hormone (PTH) levels, especially in older adults with low vitamin D, can lead to osteomalacia, increased bone turnover, reduced bone density, and a heightened risk of bone fractures.

Effects on Bone Mineral Density

Low concentrations of 25-hydroxyvitamin D (25-OH) are strongly associated with decreased bone mineral density. When assessed alongside other clinical indicators, vitamin D levels can provide valuable insights into overall bone metabolism and the risk of developing osteoporosis.

How the Body Produces and Activates Vitamin D

Vitamin D is a fat-soluble steroid hormone precursor that is primarily synthesised in the skin through exposure to sunlight. However, it is initially biologically inactive and requires two hydroxylation steps—first in the liver and then in the kidneys—to be converted into its active form, 1,25-dihydroxyvitamin D.

Private Vitamin D Testing in Slough and Nearby Areas

Individuals in Slough, Windsor, Langley, Burnham, and Maidenhead can access comprehensive private vitamin D testing to monitor bone health and assess their risk for deficiency-related conditions. Early detection through blood tests helps in the prevention and management of bone and muscle-related disorders linked to low vitamin D levels.

There is an additional £20 phlebotomy fee for every donation.