An enhanced at-home panel for people on (or considering) GLP-1 therapy, adding Vitamin B12, Vitamin D (25-OH) and Leptin to core safety checks — HbA1c, liver & pancreatic enzymes (ALT, AST, GGT, Bilirubin, Amylase, Lipase), kidney (Urea, Creatinine, Uric Acid, eGFR), thyroid (TSH, FT4), lipids (Total, HDL, LDL, Triglycerides) and FBC — to track efficacy, nutrient status and overall metabolic health.
GLP-1 medications such as semaglutide, liraglutide, and tirzepatide are transforming weight loss and type 2 diabetes care by influencing appetite, glucose control, and metabolism. Alongside intensive weight-loss programmes, however, these changes can also impact nutrient levels and organ function.
The Weight Loss / GLP-1 Profile Plus expands on our standard GLP-1 panel by including Vitamin B12, Vitamin D, and Leptin, giving a more complete picture of your nutrient sufficiency, appetite signalling, and overall metabolic response.
Vitamin B12 — Essential for energy, neurological health, and red blood cell production; may fall with restricted intake or certain medications.
Vitamin D (25-OH) — Supports immunity, bone strength, and metabolism; deficiency is common during rapid weight change.
Leptin — A key hormone regulating appetite and fat metabolism; abnormal patterns may reflect metabolic resistance or adaptation.
HbA1c — Measures average glucose over 2–3 months, helping track diabetes risk and treatment effect.
ALT, AST, GGT, Total Bilirubin — Monitor liver stress or bile duct issues.
Amylase, Lipase — Pancreatic enzymes; elevations may signal irritation or inflammation.
Urea, Creatinine, Uric Acid, eGFR — Check kidney function to ensure GLP-1 therapy is well tolerated.
TSH, Free T4 (FT4) — Thyroid balance impacts weight regulation, energy, and mood.
Total Cholesterol, HDL, LDL, Triglycerides — Track cardiometabolic health during weight management.
Full Blood Count (FBC) — Screens for anaemia, infection, or inflammation affecting energy and overall wellbeing.
Individuals using or starting GLP-1 medications for weight loss or type 2 diabetes
People experiencing rapid weight change, fatigue, or nutrient concerns
Those managing obesity, pre-diabetes, or metabolic syndrome
Anyone seeking a comprehensive, medically guided weight-loss health check
This expanded profile provides a comprehensive view of safety and effectiveness, helping to:
Confirm treatment response to GLP-1 therapy
Identify nutrient deficiencies (Vitamin B12, Vitamin D) early
Assess appetite hormone (Leptin) signalling
Monitor liver, kidney, pancreas, and cardiovascular health
Support tailored adjustments in diet, medication, or lifestyle for sustainable results
Order online securely
Visit your nearest Vitalync Diagnosis partner blood draw clinic for sample collection (no GP referral required)
Post your kit back to our accredited UK laboratory using the prepaid pack
Receive results securely online, via email
Important Notes
Your clinician may recommend morning sampling and fasting (especially for lipid testing).
Always follow medication timing and test preparation instructions.
Results support assessment but should be reviewed with a healthcare professional.