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NK Cell Cytotoxicity Assay

The Natural Killer (NK) cell cytotoxicity test evaluates the ability of NK cells to kill infected or cancerous cells. NK cells are essential components of the immune system, responsible for identifying and destroying abnormal cells. This test measures NK cell function, providing insights into immune health, chronic infections, and cancer surveillance. Why it is important to check this marker: Assessing NK cell cytotoxicity helps detect immune system weaknesses, chronic infections, or potential cancer risks. Low NK cell activity may indicate an increased susceptibility to infections or tumors. Indications for testing: - Cancer surveillance: To evaluate NK cell activity in detecting and destroying cancerous cells. - Chronic infections: To assess NK cell function in conditions like HIV, herpes, or chronic viral infections. - Immunodeficiency: To identify weakened immune function in patients with frequent infections. - Autoimmune conditions: To monitor NK cell activity in autoimmune disorders. What can be detected: - Immune dysfunction: Low NK cell activity may indicate immune system impairment. - Chronic infections or cancer: Reduced NK cell cytotoxicity can suggest an inability to fight infections or tumors. - Autoimmune or inflammatory diseases: Abnormal NK cell activity can be associated with immune dysregulation. The NK Cell Cytotoxicity Test is crucial for assessing immune system function, detecting infections, and identifying potential cancer risks, helping guide treatment decisions.

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