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NK Cells (CD3/CD16/CD56)

The NK Cells (CD3/CD16/CD56) panel measures natural killer (NK) cells by analyzing key surface markers: CD3: Identifies T-cells and helps differentiate NK cells from other immune cells. CD16: Assesses NK cell cytotoxicity, indicating the ability to kill infected or tumor cells. CD56: Marks the presence of NK cells, helping to evaluate their function in immune responses. Why it is important to check these markers: Measuring NK cells helps assess immune system activity, detect immune deficiencies, and evaluate the body’s ability to fight infections and tumors. Abnormal NK cell levels may indicate immune dysfunction or increased susceptibility to disease. Indications for testing: - Cancer surveillance: To monitor NK cell activity in fighting tumors. - Chronic infections: Assess NK cell function in conditions like HIV, Epstein-Barr virus (EBV), or chronic hepatitis. - Immune deficiencies: Identify immune system weaknesses in patients with frequent infections. - Autoimmune diseases: Monitor NK cell activity in autoimmune conditions like rheumatoid arthritis or lupus. What can be detected: - Immune dysfunction: Low NK cell levels or abnormal function can indicate immune system deficiencies. - Chronic infections or cancer: Reduced NK cell activity may suggest an inability to fight infections or tumors. - Autoimmune disorders: Abnormal NK cell numbers may be linked to immune system dysregulation. The NK Cells (CD3/CD16/CD56) Test provides essential insights into immune health, helping diagnose infections, autoimmune diseases, and cancer risks, and guide treatment decisions.

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